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2025 Vol.30, Issue 6 Preview Page
Enhanced Bio-Electrodegradation of Acetylsalicylic Acid: Optimization, Pathway Elucidation, and Environmental Application

아세틸살리실산의 향상된 생물전기분해: 최적화, 분해 경로 규명 및 환경적 적용

Harshavardhan Mohan1
,
Pavithra Muthukumar Sathya1
,
Min-Ju Kim1
,
Bongkyu Kim1*
,
Byung-Taek Oh1*
하샤 발단모한 1
,
무투쿠마르 사티아 파비트라 1
,
김민주 1
,
김봉규 1*
,
오병택 1*
1Division of Biotechnology, Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan, Jeonbuk State 54596, Republic of Korea
1전북대학교 생명공학부
*Corresponding Author
31 December 2025. pp. 109-117
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Abstract

The widespread use and environmental persistence of acetylsalicylic acid (ASA), a commonly consumed pharmaceutical, necessitate the development of efficient and sustainable removal strategies. This study investigates the degradation of ASA using a bio-electrochemical system (BES) employing Pseudomonas putida ASP-7, isolated from animal hospital waste. Comparative assessments revealed that bio-electrodegradation achieved significantly higher removal efficiency (98.7%) than biodegradation (59.54%) and electrodegradation (12.55%), with superior degradation kinetics and half-life. Optimization experiments identified ideal conditions at 20 mV applied potential, pH 6.5, and 26-30 °C using 100 mg/L ASA. Metabolic analysis showed ASA was initially hydrolyzed to salicylic acid and catechol, which further degraded into non-toxic end products. When applied to ASA-spiked river water, the system achieved 87.51% removal, demonstrating its practical potential for real-world pharmaceutical pollutant remediation.

Keywords
Acetylsalicylic acid
Bio-electrochemical system
Degradation
Metabolic pathway
Pseudomonas putida
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Information
  • Publisher :The Korean Society of Soil and Groundwater Environment
  • Publisher(Ko) :한국지하수토양환경학회
  • Journal Title :Journal of Soil and Groundwater Environment
  • Journal Title(Ko) :지하수토양환경
  • Volume : 30
  • No :6
  • Pages :109-117
  • Received Date : 2025-11-27
  • Revised Date : 2025-12-12
  • Accepted Date : 2025-12-23
  • DOI :https://doi.org/10.7857/JSGE.2025.30.6.109
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